Acetyl l-carnitine also referred to as (ALCAR) is a form of carnitine that is naturally produced by the body. The main purpose of acetyl l-carnitine is to assist in cell metabolism where fatty is broken down by cells to form ATP (energy used by cells). So by assisting in cell metabolism, mitochondria in the cells can function at their optimum levels improving efficiency of the body at a molecular level.
New research has shown that when acetyl l-carnitine is combined with ALA, an interesting thing happens. The results from the study showed that in rats it has fascinating anti aging effects. What was truly interesting is how the combination of the 2 substances worked to achieve these results.
During the energy transfer process by the cells waste is produced that can build up and another responsibility of carnitine is to help remove those waste products. Supplementation of carnitine can improve mitochondrial energy in healthy individuals but is also very beneficial to those with liver, kidney or some other disease that prevents the body from producing this substance.
As cells age, the functions performed by the mitochondria begin to slow down. Studies suggest that acetyl-L-carnitine can reverse the defects within cells thereby improving function of the cell and signs of aging.
Acetyl L-Carnitine Effects on Alzheimer’s Disease
One of acetyl l-carnitine’s properties is the ability to pass through the blood brain barrier. There are few substances that have the ability to do this which gives carnitine its open door to be effective on Alzheimer’s disease. One study showed a significant amount of protection against deterioration in brain activity.
Carnitine and Diabetes
Acetyl-L-carnitine improved the regeneration of nerve fibers which nearly doubled. One of the complications presented by diabetes is the sensitivity reduction of nerves. This shows that it can have a direct effect on the complications of the disease.
Intestinal and neurological complications are very common in diabetic patients. One study done in Switzerland showed that it dramatically decreased a certain polypeptide in the intestines. Suggesting that acetyl-L-carnitine could be effective in the treatment of nerve disorders.
Information on the study can be seen here on alpha lipoic acid anti aging. Without this form of carnitine in conjunction, the study would be no where near as effective.
“Primary preventive and secondary interventionary effects of acetyl-L- carnitine on diabetic neuropathy…”
Journal of Clinical Investigation (USA), 1996
“Clinical and neurochemical effects of acetyl-L-carnitine in Alzheimer’s disease”
University of Pittsburgh, School of Medicine